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January 8, 1920 – December 17, 2015, was a Japanese biochemist, physiologist, and military physician. He discovered Oxygenases at the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health in 1955.
Citing his "outstanding and pioneering contributions to biomedical sciences and enzymology," the Wolf Foundation awarded Hayaishi the 1986 Wolf Prize in Medicine "for his discovery of the oxygenase enzymes and elucidation of their structure and biological importance". The Wolf Prize in Medicine
Hayaishi was President of International Union of Biochemistry and Molecular Biology from 1973 to 1976.
After working with Arthur Kornberg at the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health and Washington University in St. Louis, Hayaishi served as a research group leader or a professor at various research institutions in the US and Japan including Kyoto University, and led approximately 600 graduate students in his life including Yasutomi Nishizuka; Tasuku Honjo, the 2018 Nobel laureate in medicine or physiology; and Shigetada Nakanishi. More than 100 of his pupils became professors at various universities in Japan. "運・鈍・根 酸素添加酵素と睡眠" Biography of Osamu Hayaishi
Hayaishi is also known for his discovery of the sleep-inducing action of Prostaglandin D2.
He was also elected as a foreign member of several academies, as well as a member of the Japan Academy (MJA) in 1974.
In 1984, he was made an honorary citizen of Kyoto.
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